At Mediasmiths we use both Trello and JIRA for managing development and support tickets. JIRA has some advantages when it comes to creating formal structures, but for smaller projects, or when there are fewer dependencies to keep track of, we think Trello is a great little tool. And we love horizontal scrolling on Kanban boards! Are you listening, Atlassian?
Here are the very simple guidelines we use for managing tickets in Trello.